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★★★★★
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USD 100 /hr
Hire Dr. Paul D.
United Kingdom
USD 100 /hr

Life Sciences & Technology Innovator and Academic

Profile Summary
Subject Matter Expertise
Services
Writing Non-Medical Regulatory Writing
Research Feasibility Study
Consulting Business Strategy Consulting, Go-to-Market Strategy Consulting
Work Experience

Co-founder, Scientific Director

Stroma Therapeutics

February 2020 - Present

Honorary Reader (2021-present), Reader (2013- 2021), Senior Research Fellow (2005-2013)

University of Edinburgh

September 2005 - Present

Group Leader

Roslin Institute

September 1998 - July 2005

Post-doctoral Fellow

University of Western Ontario Department of Medicine

September 1995 - July 1998

Post-doctoral fellow

University of Pennsylvania

January 1994 - August 1995

Postdoctoral Fellow

University of Toronto

September 1993 - December 1993

Education

PhD (Zoology)

University of Western Ontario Faculty of Science

January 1989 - August 1993

Master of Science (Zoology)

University of Toronto

September 1986 - May 1989

(Honours) Bachelor of Sciences

University of Toronto

September 1982 - May 1986

Certifications
  • Certification details not provided.
Publications
JOURNAL ARTICLE
Eirini Koutsouraki, Steve Pells, Paul A. De Sousa(2019). Sufficiency of hypoxia-inducible 2-oxoglutarate dioxygenases to block chemical oxidative stress-induced differentiation of human embryonic stem cells . Stem Cell Research. 34. p. 101358. Elsevier {BV}
De Sousa, P.A., Ritchie, D., Green, A., Chandran, S., Knight, R., Head, M.W.(2019). Renewed assessment of the risk of emergent advanced cell therapies to transmit neuroproteinopathies . Acta Neuropathologica. 137. (3). p. 363-377.
De Sousa PA, Ritchie D, Green A, Chandran S, Knight R, Head MW(2018). Renewed assessment of the risk of emergent advanced cell therapies to transmit neuroproteinopathies . Acta neuropathologica.
Paul A. De Sousa, Rachel Steeg, Beate Kreisel, Timothy E. Allsopp(2017). Hot Start to European Pluripotent Stem Cell Banking . Trends in Biotechnology. 35. (7). p. 573--576. Elsevier {BV}
Paul A. De Sousa, Rachel Steeg, Elisabeth Wachter, Kevin Bruce, Jason King, Marieke Hoeve, Shalinee Khadun, George McConnachie, Julie Holder, Andreas Kurtz, et al.(2017). Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience . Stem Cell Research. 20. p. 105--114. Elsevier {BV}
De Sousa, P.A., Steeg, R., Wachter, E., Bruce, K., King, J., Hoeve, M., Khadun, S., McConnachie, G., Holder, J., Kurtz, A., et al.(2017). Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience . Stem Cell Research. 20. p. 105-114.
De Sousa, P.A., Steeg, R., Kreisel, B., Allsopp, T.E.(2017). Hot Start to European Pluripotent Stem Cell Banking . Trends in Biotechnology. 35. (7). p. 573-576.
P.A. De Sousa, J.M. Downie, B.J. Tye, K. Bruce, P. Dand, S. Dhanjal, P. Serhal, J. Harper, M. Turner, M. Bateman(2016). Development and production of good manufacturing practice grade human embryonic stem cell lines as source material for clinical application . Stem Cell Research. 17. (2). p. 379--390. Elsevier {BV}
Davis MR, Arner E, Duffy CR, De Sousa PA, Dahlman I, Arner P, Summers KM(2016). Datasets of genes coexpressed with FBN1 in mouse adipose tissue and during human adipogenesis . Data in brief.
P.A. De Sousa, B.J. Tye, K. Bruce, P. Dand, G. Russell, D.M. Collins, A. Greenshields, K. McDonald, H. Bradburn, A. Laurie, et al.(2016). Derivation of the clinical grade human embryonic stem cell line RCe018-A (RC-14) . Stem Cell Research. Elsevier {BV}
P.A. De Sousa, B.J. Tye, K. Bruce, P. Dand, G. Russell, D.M. Collins, A. Greenshields, K. McDonald, H. Bradburn, A. Laurie, et al. (2016). Derivation of the clinical grade human embryonic stem cell line RCe017-A (RC-13) . Stem Cell Research.
P.A. De Sousa, B.J. Tye, K. Bruce, P. Dand, G. Russell, D.M. Collins, A. Greenshields, H. Bradburn, J.M. Downie, M. Bateman, et al.(2016). Derivation of the human embryonic stem cell line RCe014-A (RC-10) . Stem Cell Research. 16. (2). p. 537--540. Elsevier {BV}
N. A. Willoughby, H. Bock, M. A. Hoeve, S. Pells, C. Williams, G. McPhee, P. Freile, D. Choudhury, P. A. De Sousa(2016). A scalable label-free approach to separate human pluripotent cells from differentiated derivatives . Biomicrofluidics. 10. (1). p. 014107. {AIP} Publishing
De Sousa, P.A., Tye, B.J., Bruce, K., Dand, P., Russell, G., Collins, D.M., Greenshields, A., McDonald, K., Bradburn, H., Laurie, A., et al.(2016). Derivation of the clinical grade human embryonic stem cell line RCe015-A (RC-11) . Stem Cell Research. 17. (1). p. 42-48.
De Sousa, P.A., Tye, B.J., Bruce, K., Dand, P., Russell, G., Collins, D.M., Greenshields, A., McDonald, K., Bradburn, H., Canham, M.A., et al.(2016). Derivation of the clinical grade human embryonic stem cell line RCe013-A (RC-9) . Stem Cell Research. 17. (1). p. 36-41.
De Sousa, P.A., Tye, B.J., Bruce, K., Dand, P., Russell, G., Collins, D.M., Greenshields, A., Bradburn, H., Downie, J.M., Bateman, M., et al.(2016). Derivation of the human embryonic stem cell line RCe014-A (RC-10) . Stem Cell Research. 16. (2). p. 537-540.
Willoughby, N.A., Bock, H., Hoeve, M.A., Pells, S., Williams, C., McPhee, G., Freile, P., Choudhury, D., De Sousa, P.A.(2016). A scalable label-free approach to separate human pluripotent cells from differentiated derivatives . Biomicrofluidics. 10. (1).
De Sousa, P.A., Tye, B.J., Bruce, K., Dand, P., Russell, G., Collins, D.M., Greenshields, A., McDonald, K., Bradburn, H., Allan, D., et al.(2016). Derivation of the clinical grade human embryonic stem cell line RCe021-A (RC-17) . Stem Cell Research. 17. (1). p. 1-5.
De Sousa, P.A., Tye, B.J., Bruce, K., Dand, P., Russell, G., Collins, D.M., Greenshields, A., Bradburn, H., Downie, J.M., Bateman, M., et al.(2016). Derivation of the human embryonic stem cell line RCe012-A (RC-8) . Stem Cell Research. 16. (2). p. 489-492.
De Sousa, P.A., Tye, B.J., Collins, D.M., Bruce, K., Dand, P., Russell, G., Bradburn, H., Downie, J.M., Bateman, M., Courtney, A.(2016). Derivation of the human embryonic stem cell line RCe011-A (RC-7) . Stem Cell Research. 16. (2). p. 485-488.
De Sousa, P.A., Tye, B., Bruce, K., Dand, P., Russell, G., Collins, D.M., Gardner, J., Downie, J.M., Bateman, M., Courtney, A.(2016). Derivation of the human embryonic stem cell line RCe009-A (RC-5) . Stem Cell Research. 16. (2). p. 418-422.
De Sousa, P.A., Tye, B.J., Bruce, K., Dand, P., Russell, G., Collins, D.M., Bradburn, H., Gardner, J., Downie, J.M., Bateman, M., et al.(2016). Derivation of the human embryonic stem cell line RCe010-A (RC-6) . Stem Cell Research. 16. (2). p. 481-484.
De Sousa, P.A., Tye, B., Bruce, K., Dand, P., Russell, G., Gardner, J., Downie, J.M., Bateman, M., Courtney, A.(2016). Derivation of the human embryonic stem cell line RCe006-A (RC-2) . Stem Cell Research. 16. (2). p. 452-455.
De Sousa, P.A., Tye, B.J., Sneddon, S., Bruce, K., Dand, P., Russell, G., Collins, D.M., Greenshields, A., McDonald, K., Bradburn, H., et al.(2016). Derivation of the human embryonic stem cell line RCM1 . Stem Cell Research. 16. (2). p. 476-480.
De Sousa, P.A., Tye, B.J., Bruce, K., Dand, P., Russell, G., Collins, D.M., Greenshields, A., McDonald, K., Bradburn, H., Laurie, A., et al.(2016). Derivation of the clinical grade human embryonic stem cell line RCe017-A (RC-13) . Stem Cell Research. 16. (3). p. 756-760.
De Sousa, P.A., Tye, B., Bruce, K., Dand, P., Gardner, J., Downie, J.M., Bateman, M., Courtney, A.(2016). Derivation of the human embryonic stem cell line RCe008-A (RC-4) . Stem Cell Research. 16. (3). p. 607-610.
De Sousa, P.A., Tye, B., Bruce, K., Dand, P., Russell, G., Gardner, J., Downie, J.M., Bateman, M., Courtney, A.(2016). Derivation of the human embryonic stem cell line RCe007-A (RC-3) . Stem Cell Research. 16. (3). p. 593-596.
De Sousa, P.A., Tye, B.J., Bruce, K., Dand, P., Russell, G., Collins, D.M., Greenshields, A., McDonald, K., Bradburn, H., Laurie, A., et al.(2016). Derivation of the clinical grade human embryonic stem cell line RCe020-a (RC-16) . Stem Cell Research. 16. (3). p. 790-794.
De Sousa, P.A., Tye, B.J., Bruce, K., Dand, P., Russell, G., Collins, D.M., Greenshields, A., McDonald, K., Bradburn, H., Laurie, A., et al.(2016). Derivation of the clinical grade human embryonic stem cell line RCe019-A (RC-15) . Stem Cell Research. 16. (3). p. 751-755.
Davis, M.R., Arner, E., Duffy, C.R.E., De Sousa, P.A., Dahlman, I., Arner, P., Summers, K.M.(2016). Expression of FBN1 during adipogenesis: Relevance to the lipodystrophy phenotype in Marfan syndrome and related conditions . Molecular Genetics and Metabolism. 119. (1-2). p. 174-185.
De Sousa, P.A., Tye, B.J., Bruce, K., Dand, P., Russell, G., Collins, D.M., Greenshields, A., McDonald, K., Bradburn, H., Laurie, A., et al.(2016). Derivation of the clinical grade human embryonic stem cell line RCe016-A (RC-12) . Stem Cell Research. 16. (3). p. 770-775.
Davis, M.R., Arner, E., Duffy, C.R.E., De Sousa, P.A., Dahlman, I., Arner, P., Summers, K.M.(2016). Datasets of genes coexpressed with FBN1 in mouse adipose tissue and during human adipogenesis . Data in Brief. 8. p. 851-857.
De Sousa, P.A., Downie, J.M., Tye, B.J., Bruce, K., Dand, P., Dhanjal, S., Serhal, P., Harper, J., Turner, M., Bateman, M.(2016). Development and production of good manufacturing practice grade human embryonic stem cell lines as source material for clinical application . Stem Cell Research. 17. (2). p. 379-390.
Mangani, C., Lilienkampf, A., Roy, M., De Sousa, P.A., Bradley, M.(2015). Thermoresponsive hydrogel maintains the mouse embryonic stem cell "naïve" pluripotency phenotype . Biomaterials Science. 3. (10). p. 1371-1375.
Pells, S., Koutsouraki, E., Morfopoulou, S., Valencia-Cadavid, S., Tomlinson, S.R., Kalathur, R., Futschik, M.E., De Sousa, P.A.(2015). Novel Human Embryonic Stem Cell Regulators Identified by Conserved and Distinct CpG Island Methylation State . PloS one. 10. (7). p. e0131102.
Canham, M.A., Van Deusen, A., Brison, D.R., De Sousa, P.A., Downie, J., Devito, L., Hewitt, Z.A., Ilic, D., Kimber, S.J., Moore, H.D., et al.(2015). The Molecular Karyotype of 25 Clinical-Grade Human Embryonic Stem Cell Lines . Scientific Reports. 5.
Andrews, P.W., Baker, D., Benvinisty, N., Miranda, B., Bruce, K., Brüstle, O., Choi, M., Choi, Y.-M., Crook, J.M., De Sousa, P.A., et al.(2015). Points to consider in the development of seed stocks of pluripotent stem cells for clinical applications: International Stem Cell Banking Initiative (ISCBI) . Regenerative Medicine. 10. p. 1-44.
Krejciova, Z., De Sousa, P., Manson, J., Ironside, J.W., Head, M.W.(2014). Human tonsil-derived follicular dendritic-like cells are refractory to human prion infection in vitro and traffic disease-associated prion protein to lysosomes . American Journal of Pathology. 184. (1). p. 64-70.
Yan, X., Ehnert, S., Culmes, M., Bachmann, A., Seeliger, C., Schyschka, L., Wang, Z., Rahmanian-Schwarz, A., Stöckle, U., De Sousa, P.A., et al.(2014). 5-azacytidine improves the osteogenic differentiation potential of aged human adipose-derived mesenchymal stem cells by DNA demethylation . PLoS ONE. 9. (3).
Hansen, A., Mjoseng, H.K., Zhang, R., Kalloudis, M., Koutsos, V., de Sousa, P.A., Bradley, M.(2014). High-Density Polymer Microarrays: Identifying Synthetic Polymers that Control Human Embryonic Stem Cell Growth . Advanced Healthcare Materials. 3. (6). p. 848-853.
Duffy, C.R.E., Zhang, R., How, S.-E., Lilienkampf, A., Tourniaire, G., Hu, W., West, C.C., De Sousa, P., Bradley, M.(2014). A high-throughput polymer microarray approach for identifying defined substrates for mesenchymal stem cells . Biomaterials Science. 2. (11). p. 1683-1692.
Duffy, C.R.E., Zhang, R., How, S.-E., Lilienkampf, A., De Sousa, P.A., Bradley, M.(2014). Long term mesenchymal stem cell culture on a defined synthetic substrate with enzyme free passaging . Biomaterials. 35. (23). p. 5998-6005.
Tsenkina, Y., Ruzov, A., Gliddon, C., Horsburgh, K., De Sousa, P.A.(2014). White matter tract and glial-associated changes in 5-hydroxymethylcytosine following chronic cerebral hypoperfusion . Brain Research. 1592. p. 82-100.
Krause, K.-H., Van Thriel, C., De Sousa, P.A., Leist, M., Hengstler, J.G.(2013). Monocrotophos in Gandaman village: India school lunch deaths and need for improved toxicity testing . Archives of Toxicology. 87. (10). p. 1877-1881.
Armit, Chris, Bauer, Nina G., Besseling, Rut, Bradley, Mark, Duffy, Cairnan R. E., Edenhofer, Frank, Helfen, Martina, Hoeve, Marieke A., Kishen, Ria E. B., Mjoseng, Heidi K., et al.(2013). A thermoresponsive and chemically defined hydrogel for long-term culture of human embryonic stem cells . Nature Communications. 4.
Zhang, R., Mjoseng, H.K., Hoeve, M.A., Bauer, N.G., Pells, S., Besseling, R., Velugotla, S., Tourniaire, G., Kishen, R.E.B., Tsenkina, Y., et al.(2013). A thermoresponsive and chemically defined hydrogel for long-term culture of human embryonic stem cells . Nature Communications. 4.
Anstee, D., Courtney, A., Forrester, L., Mountford, J., Murphy, W., Newlands, H., Parsons, S., Pelly, J., Turner, M. L., de Sousa, P.(2013). PROGRESS TOWARDS THE CGMP PRODUCTION OF PLURIPOTENT STEM CELL DERIVED RED BLOOD CELLS. Cytotherapy. 15. (4). p. S7.
Bradley, Mark, De Sousa, Paul A., Ermakov, Alexander, Freile, Paz, Ganeva, Veronika V., Millar, Robert, Pawson, Adam, Pells, Steve, Wildenhain, Jan(2012). A role for intracellular calcium downstream of G-protein signaling in undifferentiated human embryonic stem cell culture . Stem Cell Research. 9. (3). p. 171-184.
Ermakov, A., Pells, S., Freile, P., Ganeva, V.V., Wildenhain, J., Bradley, M., Pawson, A., Millar, R., De Sousa, P.A.(2012). A role for intracellular calcium downstream of G-protein signaling in undifferentiated human embryonic stem cell culture . Stem Cell Research. 9. (3). p. 171-184.
Damm, G., Ehnert, S., Martinez Sanchez, J. J., Nuessler, A., Stoeckle, U., Yan, X., de Sousa, P.(2012). CHEMICAL MODIFICATION EPIGENETICALLY 'RENEWS' OLD HUMAN ADIPOSE DERIVED MESENCHYMAL STEM CELLS AND IMPROVES THEIR DIFFERENTIATION INTO HEPATOCYTES LINEAGE. Journal of Hepatology. 56. p. S173.
De Sousa, Paul, Duffy, Cairnan R. E., Mjoseng, Heidi K., Pells, Steve, Pethig, Ronald, Smith, Stewart, Velugotla, Srinivas(2012). Dielectrophoresis based discrimination of human embryonic stem cells from differentiating derivatives . Biomicrofluidics. 6. (4).
Bagnaninchi, Pierre, Corradetti, Bruna, Fahmy, Tarek M., Freile, Paz, Park, Jason, Pells, Steve, de Sousa, Paul A.(2012). Paracrine signalling events in embryonic stem cell renewal mediated by affinity targeted nanoparticles . Biomaterials. 33. (28). p. 6634-6643.
Velugotla, S., Pells, S., Mjoseng, H.K., Duffy, C.R.E., Smith, S., De Sousa, P., Pethig, R.(2012). Dielectrophoresis based discrimination of human embryonic stem cells from differentiating derivatives . Biomicrofluidics. 6. (4).
Corradetti, B., Freile, P., Pells, S., Bagnaninchi, P., Park, J., Fahmy, T.M., de Sousa, P.A.(2012). Paracrine signalling events in embryonic stem cell renewal mediated by affinity targeted nanoparticles . Biomaterials. 33. (28). p. 6634-6643.
McVean, Gilean, Murphy, Lee, Robertson, Victoria, Turner, David M., de Sousa, Paul(2012). SNP SCREENING FOR HLA HAPLOTYPES RELEVANT IN ESTABLISHING A HUMAN PLURIPOTENT STEM CELL DERIVED CELL BANK. Tissue Antigens. 79. (6). p. 540-541.
Almeida, Rimple D., De Sousa, Paul A., Johnson, Andrew D., Loose, Matthew, Ruzov, Alexey, Sottile, Virginie(2012). Semi-quantitative immunohistochemical detection of 5-hydroxymethyl-cytosine reveals conservation of its tissue distribution between amphibians and mammals . Epigenetics. 7. (2). p. 137-140.
Almeida, R.D., Sottile, V., Loose, M., De Sousa, P.A., Johnson, A.D., Ruzov, A.(2012). Semi-quantitative immunohistochemical detection of 5-hydroxymethyl-cytosine reveals conservation of its tissue distribution between amphibians and mammals . Epigenetics. 7. (2). p. 137-140.
Adya, Ashok K., Bock, Henry, Canetta, Elisabetta, De Sousa, Paul, Kiss, Robert, Moore, Andrew J., Pells, Steve, Willoughby, Nicholas A.(2011). Elasticity of Human Embryonic Stem Cells as Determined by Atomic Force Microscopy . Journal of Biomechanical Engineering-Transactions of the Asme. 133. (10).
Courtney, A., De Sousa, P., George, C., Laurie, G., Tait, J.(2011). Balancing open source stem cell science with commercialization . Nature Biotechnology. 29. (2). p. 115-116.
Adya, Ashok K, Bock, Henry, Canetta, Elisabetta, De Sousa, Paul, Kiss, Robert, Moore, Andrew J, Pells, Steve, Willoughby, Nicholas A(2011). Elasticity of human embryonic stem cells as determined by atomic force microscopy . Journal of biomechanical engineering. 133. (10). p. 101009.
Kiss, R., Bock, H., Pells, S., Canetta, E., Adya, A.K., Moore, A.J., De Sousa, P., Willoughby, N.A.(2011). Elasticity of human embryonic stem cells as determined by atomic force microscopy . Journal of Biomechanical Engineering. 133. (10).
Barclay, G. Robin, Bishop, Matthew, Cancellotti, Enrico, De Sousa, Paul, Freile, Paz, Head, Mark W., Ironside, James W., Krejciova, Zuzana, Manson, Jean C., Pells, Steve, et al.(2011). Human embryonic stem cells rapidly take up and then clear exogenous human and animal prions in vitro . Journal of Pathology. 223. (5). p. 635-645.
Krejciova, Z., Pells, S., Cancellotti, E., Freile, P., Bishop, M., Samuel, K., Barclay, G.R., Ironside, J.W., Manson, J.C., Turner, M.L., et al.(2011). Human embryonic stem cells rapidly take up and then clear exogenous human and animal prions in vitro . Journal of Pathology. 223. (5). p. 635-645.
Bai, Yu, Bradley, Mark, Chandran, Siddharthan, Chebotareva, Tatiana, De Sousa, Paul, Dudnakova, Tatiana, Fletcher, Judy, Hannoun, Zara, Hay, David C., Pells, Steve, et al.(2011). Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development . Cell Research. 21. (9). p. 1332-1342.
Ruzov, A., Tsenkina, Y., Serio, A., Dudnakova, T., Fletcher, J., Bai, Y., Chebotareva, T., Pells, S., Hannoun, Z., Sullivan, G., et al.(2011). Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development . Cell Research. 21. (9). p. 1332-1342.
Amps, Katherine, Andrews, Peter W., Anyfantis, George, Armstrong, Lyle, Avery, Stuart, Baharvand, Hossein, Baker, Duncan, Baker, Julie, Beil, Stephen, Ben-Yosef, Dalit, et al.(2011). Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage . Nature Biotechnology. 29. (12). p. 1132-U113.
Amps, Katherine, Andrews, Peter W, Anyfantis, George, Armstrong, Lyle, Avery, Stuart, Baharvand, Hossein, Baker, Duncan, Baker, Julie, Beil, Stephen, Ben-Yosef, Dalit, et al.(2011). Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage . Nature biotechnology. 29. (12). p. 1132-44.
Amps, K., Andrews, P.W., Anyfantis, G., Armstrong, L., Avery, S., Baharvand, H., Baker, J., Baker, D., Munoz, M.B., Beil, S., et al.(2011). Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage . Nature Biotechnology. 29. (12). p. 1132-1144.
Saft, C., Epplen, Wieczorek, S., Landwehrmeyer, G.B., Roos, R.A.C., de Yebenes, J.G., Dose, M., Tabrizi, S.J., Craufurd, D., Arning, L., et al.(2011). NMDA receptor gene variations as modifiers in Huntington disease: A replication study . PLoS Currents.
Abbruzzese, Giovanni, Aguilar Barbera, Miquel, Albanese, Alberto, Andrews, Thomasin, Andrich, Jurgen, Antczak, Jakub, Arran, Natalie, Bachoud-Levi, A -C, Badenes, Dolores, Banaszkiewicz, Krzystof, et al.(2010). Observing Huntington's Disease: the European Huntington's Disease Network's REGISTRY . PLoS currents.
Mountford, J.C., Olivier, E., Jordanides, N.E., De Sousa, P., Turner, M.L.(2010). Red blood cells from pluripotent stem cells for use in transfusion . Regenerative Medicine. 5. (3). p. 411-423.
De Sousa, Paul, Menachery, Anoop, Pells, Steve, Pethig, Ronald(2010). Dielectrophoresis: a review of applications for stem cell research . Journal of biomedicine & biotechnology. 2010. p. 182581.
De Sousa, Paul, Menachery, Anoop, Pells, Steve, Pethig, Ronald(2010). Dielectrophoresis: A Review of Applications for Stem Cell Research . Journal of Biomedicine and Biotechnology.
Anderson, Richard A., Bayne, Rosemary A. L., De Sousa, Paul A., Gardner, John(2010). Brain-derived neurotrophic factor is a regulator of human oocyte maturation and early embryo development . Fertility and Sterility. 93. (5). p. 1394-1406.
Anderson, R.A., Bayne, R.A.L., Gardner, J., De Sousa, P.A.(2010). Brain-derived neurotrophic factor is a regulator of human oocyte maturation and early embryo development . Fertility and Sterility. 93. (5). p. 1394-1406.
Pethig, R., Menachery, A., Pells, S., De Sousa, P.(2010). Dielectrophoresis: A review of applications for stem cell research . Journal of Biomedicine and Biotechnology. 2010.
Jordanides, Niove E., Mountford, Joanne C., Oliver, Emmanuel, Turner, Marc L., de Sousa, Paul(2010). Red blood cells from pluripotent stem cells for use in transfusion . Regenerative Medicine. 5. (3). p. 411-423.
Brison, Daniel R., Collins, Daniel M., Cooke, Michael, Dand, Pawlina, De Sousa, Paul A., Gardner, John, Kimber, Susan J., Lieberman, Brian A., McLaughlin, K. John, Pells, Steve, et al.(2009). Clinically failed eggs as a source of normal human embryo stem cells . Stem Cell Research. 2. (3). p. 188-197.
Ahrlund-Richter, Lars, Alvarez, Manuel, Andrews, Peter W., Arias-Diaz, Javard, Auerbach, Jonathan, Baker, Duncan, Ben-Josef, Dalit, Benvenisty, Nissim, Blin, Guillaume, Borghese, Lodovica, et al.(2009). Consensus Guidance for Banking and Supply of Human Embryonic Stem Cell Lines for Research Purposes . Stem Cell Reviews and Reports. 5. (4). p. 301-314.
Anderson, R. A., Bayne, R. A. L., Kinnell, H., Pickering, S., Sciorio, R., Thong, K. J., de Sousa, P. A.(2009). Cumulus gene expression as a predictor of human oocyte fertilisation, embryo development and competence to establish a pregnancy . Reproduction. 138. (4). p. 629-637.
De Sousa, P.A., Gardner, J., Sneddon, S., Pells, S., Tye, B.J., Dand, P., Collins, D.M., Stewart, K., Shaw, L., Przyborski, S., et al.(2009). Clinically failed eggs as a source of normal human embryo stem cells . Stem Cell Research. 2. (3). p. 188-197.
Ahrlund-Richter, Lars, Alvarez, Manuel, Andrews, Peter W, Arias-Diaz, Javard, Auerbach, Jonathan, Baker, Duncan, Ben-Josef, Dalit, Benvenisty, Nissim, Blin, Guillaume, Borghese, Lodovica, et al.(2009). Consensus guidance for banking and supply of human embryonic stem cell lines for research purposes . Stem cell reviews. 5. (4). p. 301-14.
Anderson, R.A., Sciorio, R., Kinnell, H., Bayne, R.A.L., Thong, K.J., De Sousa, P.A., Pickering, S.(2009). Cumulus gene expression as a predictor of human oocyte fertilisation, embryo development and competence to establish a pregnancy . Reproduction. 138. (4). p. 629-637.
Courtney, A., De Sousa, P. A., Turner, M.(2008). The road to delivery of human embryo stem cell-based therapies. Journal of Neurology Neurosurgery and Psychiatry. 79. p. A29.
De Sousa, Paul A., Wilmut, Ian(2007). Human parthenogenetic embryo stem cells: Appreciating what you have when you have it . Cell Stem Cell. 1. (3). p. 243-244.
De Sousa, P.A., Wilmut, I.(2007). Human Parthenogenetic Embryo Stem Cells: Appreciating What You Have When You Have It . Cell Stem Cell. 1. (3). p. 243-244.
De Sousa, Paul A., Galea, George, Turner, Marc(2006). The road to providing human embryo stem cells for therapeutic use: the UK experience . Reproduction. 132. (5). p. 681-689.
Brownstein, David G., De Sousa, Paul A., Delhanty, Joy, Dhanjal, Seema, Ferrier, Patricia M., Fletcher, Judy M., Gardner, John O., Harkness, Linda, Harper, Joyce, Lebkowski, Jane, et al.(2006). Variations in humanized and defined culture conditions supporting derivation of new human embryonic stem cell lines . Cloning and Stem Cells. 8. (4). p. 319-334.
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Fletcher, J.M., Ferrier, P.M., Gardner, J.O., Harkness, L., Dhanjal, S., Serhal, P., Harper, J., Delhanty, J., Brownstein, D.G., Prasad, Y.R., et al.(2006). Variations in humanized and defined culture conditions supporting derivation of new human embryonic stem cell lines . Cloning and Stem Cells. 8. (4). p. 319-334.
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De Sousa, PA, Natale, DR, Watson, AJ, Westhusin, ME(2001). Sensitivity of bovine blastocyst gene expression patterns to culture environments assessed by differential display RT-PCR . Reproduction. 122. (5). p. 687-693.
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Wrenzycki, C., De Sousa, P., Overström, E.W., Duby, R.T., Herrmann, D., Watson, A.J., Niemann, H., O'Callaghan, D., Boland, M.P.(2000). Effects of superovulated heifer diet type and quantity on relative mRNA abundances and pyruvate metabolism in recovered embryos . Journal of Reproduction and Fertility. 118. (1). p. 69-78.
Boland, MP, De Sousa, P, Duby, RT, Herrmann, D, Niemann, H, O'Callaghan, D, Overstrom, EW, Watson, AJ, Wrenzycki, C(2000). Effects of superovulated heifer diet type and quantity on relative mRNA abundances and pyruvate metabolism in recovered embryos . Journal of Reproduction and Fertility. 118. (1). p. 69-78.
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Watson, A.J., De Sousa, P., Caveney, A., Barcroft, L.C., Natale, D., Urquhart, J., Westhusin, M.E.(2000). Impact of bovine oocyte maturation media on oocyte transcript levels, blastocyst development, cell number, and apoptosis . Biology of Reproduction. 62. (2). p. 355-364.
Barcroft, LC, Caveney, A, De Sousa, P, Natale, D, Urquhart, J, Watson, AJ, Westhusin, ME(2000). Impact of bovine oocyte maturation media on oocyte transcript levels, blastocyst development, cell number, and apoptosis . Biology of Reproduction. 62. (2). p. 355-364.
De Sousa, P. A., Dobrinsky, J. R., Telfer, E. E., Wilmut, I., Zhu, J.(2000). Improving the efficiency of in vitro-matured pig oocyte activation. Theriogenology. 53. (1). p. 445.
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BOOK CHAPTER
Fraser, L., Bruce, K., Campbell, J.M., De Sousa, P.A.(2018). Quality assessment and production of human cells for clinical use . Methods in Molecular Biology. 1780. p. 607-629.
Hoeve, M.A., De Sousa, P.A., Willoughby, N.A.(2016). Challenges of Scale-up of Cell Separation and Purification Techniques . Bioprocessing for Cell Based Therapies. p. 127-165.
De Sousa, P.A., McRae, S., Stacey, G.(2012). Stem cells in the development of products for regenerative medicine . Regenerative Medicine, Stem Cells and the Liver. p. 77-97.
BOOK
Bruce, K.W., Campbell, J.D.M., De Sousa, P.(2017). Quality Assured Characterization of Stem Cells for Safety in Banking for Clinical Application . Methods in Molecular Biology. 1590. p. 79-98.