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Hire Dr. Omar S.

United States

Associate Scientific Director at Genzyme

Profile Summary

Ph. D. in Computational Chemistry. Many years of experience in applying Computational Chemistry and Cheminformatics to solve Drug Discovery problems with an emphasis in Structure-Based and Ligand-Based Drug Design. As a member of several Drug Discovery interdisciplinary teams used Molecular Modeling approaches to provide specific and successful compound design ideas to quickly improve compounds potency and selectivity resulting in a patent application. Many years of experience in developing, debugging, performance characterization and optimization of software for Cheminformatics and Computational Chemistry, specializing in HPC (High-Performance Computing) and Client/Server applications. Experience in compound and biological assay data management, relational/No-SQL/graph databases and big data technologies.

Subject Matter Expertise

• ☆ Chemistry
• ☆ Molecular Modeling
• ☆ Chemoinformatics
• ☆ Computational Chemistry
• ☆ Biochemical Assays
• ☆ Software Engineering
• ☆ Bioinformatics
• ☆ SQL

Services

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Work Experience

Senior Principal Scientist

Sanofi Genzyme

January 2009 - Present

Principal Scientist

Sunovion (United States)

2007 - 2009

Life Sciences Applications Engineer

Intel Corp

2005 - 2007

Takeda Pharmaceutical Company

2000 - 2005

Applications Engineer

Silicon Graphics International Corp

1993 - 2000

Senior Researcher

Center for Advanced Studies Research and Development

1991 - 1993

Resarcher

IBM Research

1989 - 1991

Systems Administrator

Centro de Estudios Superiores para el Procesamiento de la Informacion

1984 - 1989

Education

Ph.D. in Physical Chemistry

Universidad Nacional de la Plata Facultad de Ciencias Exactas

1983 - 1991

B.S. in Chemistry

Universidad Nacional de la Plata Facultad de Ciencias Exactas

1977 - 1982

Certifications

• Certification details not provided.

Publications

PATENT

Blackburn, Christopher and Claiborne, Christopher F and Cullis, Courtney A and Dales, Natalie A and Patana, Michael and Stirling, Matthew and Stradella, Omar and Weatherhead, Gabriel S(2011). Lactam compounds useful as protein kinase inhibitors .

JOURNAL ARTICLE

Omar G. Stradella, Giorgina Corongiu, Enrico Clementi(1993). Techniques for the compression of sequences of integer numbers and real numbers with fixed absolute precision . Journal of Computational Chemistry. 14. (6). p. 673--679. Wiley

J. V. Acrivos, O. Stradella(1993). SCF Wave functions for (CuO2)n lamella in crystal field of T?-Nd2CuO4 . International Journal of Quantum Chemistry. 46. (1). p. 55--71. Wiley

Enrico Clementi, Giorgina Corongiu, Dario Estrin, Eduardo Hollauer, Omar G. Stradella(1993). Time scales and other problems in linking simulations of simple chemical systems to more complex ones . International Journal of Quantum Chemistry. 45. (6). p. 511--544. Wiley

O.G. Stradella, S.A. Maluendes, E.A. Castro, A.H. Jubert(1990). Quantum topological description of the charge density of the ON-NO2 and ON-NSO molecules . Journal of Molecular Structure: THEOCHEM. 210. p. 169--174. Elsevier {BV}

A.H. Jubert, O.G. Stradella, S.A. Maluendes, E.A. Castro(1987). A theoretical study of the structure and vibrational spectrum of SNO, SNONO and ONSNO . Journal of Molecular Structure: THEOCHEM. 153. (3-4). p. 215--220. Elsevier {BV}

O. G. Stradella, S. A. Maluendes, E. A. Castro, A. H. Jubert(1987). Topological properties of the electronic density of CO-MgF2 and OC-MgF2 adducts . Theoretica Chimica Acta. 72. (1). p. 57--62. Springer Nature

Stradella, Omar G and Villar, Hugo O and Castro, Eduardo A(1987). Total and orbital SCF energies in open shell systems. Acta Chim. Sinica. 45. (1). p. 62–64.

Omar G. Stradella, Hugo O. Villar, Eduardo A. Castro(1986). On the density matrix definition of valency . Theoretica Chimica Acta. 70. (1). p. 67--71. Springer Nature

Omar G. Stradella, Hugo O. Villar, Eduardo A. Castro(1986). A theoretical conformational study of s-tetrathiane, s-tetroxane and their methyl derivatives . Journal of Molecular Structure: THEOCHEM. 135. p. 7--14. Elsevier {BV}

Omar G. Stradella, Eduardo A. Castro, Francisco M. Fernandez(1985). Molecular dipole moment charges from a new electronegativity scale . Inorganic Chemistry. 24. (22). p. 3631--3634. American Chemical Society ({ACS})

Villar, Hugo O and Stradella, Omar G and Cachau, Raul E and Castro, Eduardo A(1985). Some comments on the nucleation phenomena. Croat. Chem. Acta. 57. (6). p. 1417–1421.

O. Stradella, G.A. Arteca, E.A. Castro, F.M. Fernández(1983). Calculation of the hydrogen molecule by means of a parametrization obtained from the hydrogen ion-molecule . Journal de Physique Lettres. 44. (18). p. 741--753. {EDP} Sciences

OTHER

E. Clementi, G. Corongiu, O. G. Stradella(1991). Molecular Interactions and Large Molecules with KGNMOL . Modem Techniques in Computational Chemistry: MOTECC-91. p. 295--379. Springer Netherlands